Enaminones in organic synthesis: A novel synthesis of 1,3,5-trisubstituted benzene derivatives and of 2-substituted-5-aroylpyridines

被引：61

作者：

Abdel-Khalik, MM

Elnagdi, MH ^{[1
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

[2] Ain Shams Univ, Girls Coll Arts Sci & Educ, Dept Chem, Cairo, Egypt

来源：

SYNTHETIC COMMUNICATIONS | 2002年 / 32卷 / 02期

关键词：

Acidic media - Benzene derivatives - Dicarboxylates - Enaminones - Ethyl propiolate - Higher yield - Organic synthesis - Self-condensation;

D O I：

10.1081/SCC-120001996

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enaminones undergo self-condensation on reflux in acidic media yielding 1,3,5-trisubstituted benzene in very high yields. Reaction of enaminones 1a,b with ethyl propiolate affords 5-aroyl-1,3 -benzene dicarboxylate derivatives.

引用

页码：159 / 164

页数：6