Sarcopenia: Its assessment, etiology, pathogenesis, consequences and future perspectives

被引：762

作者：

Rolland, Y. ^{[1
,2
,3
]}

Czerwinski, S. ^{[4
]}

van Kan, G. Abellan ^{[3
]}

Morley, J. E. ^{[5
,6
]}

Cesari, M. ^{[7
]}

Onder, G. ^{[8
]}

Woo, J. ^{[9
]}

Baumgartner, R. ^{[10
]}

Pillard, F. ^{[11
]}

Boirie, Y. ^{[12
,13
]}

Chumlea, W. M. C. ^{[4
]}

Vellas, B. ^{[1
,2
,3
]}

机构：

[1] INSERM, U558, F-31073 Toulouse, France

[2] Univ Toulouse 3, F-31073 Toulouse, France

[3] CHU Toulouse, Dept Geriatr Med, F-31059 Toulouse, France

[4] Wright State Univ, Dept Community Hlth, Lifespan Hlth Res Ctr, Boonshoft Sch Med, Dayton, OH 45420 USA

[5] St Louis VA Med Ctr, Ctr Geriatr Res Educ & Clin, St Louis, MO USA

[6] St Louis Univ, Div Geriatr Med, St Louis, MO 63103 USA

[7] Univ Florida, Dept Aging & Geriatr Res, Inst Aging, Gainesville, FL USA

[8] Univ Cattolica Sacro Cuore, Dept Gerontol Geriatr & Physiatr Sci, I-00168 Rome, Italy

[9] Chinese Univ Hong Kong, Div Geriatr, Dept Med & Therapeut, Prince Wales Hosp, Hong Kong, Hong Kong, Peoples R China

[10] Univ Louisville, Dept Epidemiol & Populat Hlth, Sch Publ Hlth & Informat Sci, Louisville, KY 40229 USA

[11] Hop Larrey, Serv Explorat Fonct Resp & Med Sport, TSA 30030, F-31059 Toulouse 9, France

[12] Univ Clermont 1, UFR Med, UMR 1019, Unite Nutr Humaine,CRNH Auvergne, F-63001 Clermont Ferrand, France

[13] CHU Clermont Ferrand, Clin Nutr Unit, F-63001 Clermont Ferrand, France

来源：

JOURNAL OF NUTRITION HEALTH & AGING | 2008年 / 12卷 / 07期

关键词：

D O I：

10.1007/BF02982704

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 [法学]; 0303 [社会学]; 100203 [老年医学];

摘要：

Sarcopenia is a loss of muscle protein mass and loss Of muscle function. It occurs with increasing age, being a major component in the development of frailty. Current knowledge on its assessment, etiology, pathogenesis, consequences and future perspectives are reported in the present review. On-going and future clinical trials on sarcopenia may radically change our preventive and therapeutic approaches of mobility disability in older people.

引用

页码：433 / 450

页数：18

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