Selective photochemical cleavage of an α-ketoamide in a highly functionalised macrolide ascomycin

被引：4

作者：

Bulusu, MARC ^{[1
]}

Waldstätten, P ^{[1
]}

Tricotett, T ^{[1
]}

Schulz, G ^{[1
]}

机构：

[1] Novartis Inst Biomed Res, A-1235 Vienna, Austria

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 12期

关键词：

phototransformation; photochemical amide cleavage; zwitterion;

D O I：

10.1016/j.tetlet.2004.02.014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel photochemical amide cleavage reaction of (6S)-methoxyascomycin opening a pathway for the selective cleavage of the pipecolic acid, is described. The scope of this reaction with several analogues carrying suitable protecting groups is examined. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2527 / 2530

页数：4

共 27 条

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