Unnoticed spread of class 1 integrons in gram-positive clinical strains isolated in Guangzhou, China

被引:36
作者
Shi, Lei
Zheng, Meiping
Xiao, Zenghuang
Asakura, Masahiro
Su, Jianyu
Li, Lin
Yamasaki, Shinji
机构
[1] Osaka Prefecture Univ, Grad Sch Life & Environm Sci, Sakai, Osaka 5998531, Japan
[2] S China Univ Technol, Coll Food & Biol Engn, Guangzhou, Peoples R China
[3] Jinan Univ, Affiliated Hosp 1, Coll Med, Guangzhou, Peoples R China
关键词
integrons; gene cassettes; gram-positive bacteria;
D O I
10.1111/j.1348-0421.2006.tb03815.x
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
A total of 46 gram-positive bacteria isolated from clinical specimens collected in China were subjected to PCR analysis with the intI1-specific primers, and the intI1-positive strains were further analyzed for their resistance gene cassette. All isolates possessed the class 1 integron in their genomes and the array of gene cassettes was dhfrXII-orJF-aadA2, which is very similar to other organisms except in one isolate carrying an additional copy of the class 1 integron containing the aadA2 gene cassette. Altogether, the results indicate that the class 1 integron is widespread in gram-positive clinical strains isolated in Guangzhou, China.
引用
收藏
页码:463 / 467
页数:5
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