Transport vesicle docking: SNAREs and associates

被引：181

作者：

Pfeffer, SR

机构：

[1] Department of Biochemistry, Stanford University, School of Medicine, Stanford

来源：

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY | 1996年 / 12卷

关键词：

membrane traffic; intracellular transport; protein targeting; secretion;

D O I：

10.1146/annurev.cellbio.12.1.441

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Proteins that function in transport vesicle docking are being identified at a rapid rate. So-called v- and t-SNAREs form the core of a vesicle docking complex. Additional accessory proteins are required to protect SNAREs from promiscuous binding and to deprotect SNAREs under conditions in which transport vesicle docking should occur. Because access to SNAREs must be regulated, other proteins must also contain specificity determinants to accomplish delivery of transport vesicles to their distinct and specific membrane targets.

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页码：441 / 461

页数：21

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