MRSA with progression from otitis media and sphenoid sinusitis to clival osteomyelitis, pachymeningitis and abducens nerve palsy in an immunocompetent 10-year-old patient

被引：27

作者：

Laurens, Matthew B. ^{[1
]}

Becker, Randy M. ^{[2
]}

Johnson, Jennifer K. ^{[3
]}

Wolf, Jeffrey S. ^{[4
]}

Kotloff, Karen L. ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Pediat, Div Infect Dis & Trop Pediat, Baltimore, MD 21201 USA

[2] Univ Maryland, Sch Med, Dept Radiol, Baltimore, MD 21201 USA

[3] Univ Maryland, Sch Med, Dept Pathol, Baltimore, MD 21201 USA

[4] Univ Maryland, Sch Med, Dept Otorhinolaryngol Head & Neck Surg, Baltimore, MD 21201 USA

来源：

INTERNATIONAL JOURNAL OF PEDIATRIC OTORHINOLARYNGOLOGY | 2008年 / 72卷 / 07期

关键词：

sphenoidotomy; pachymeningitis; nerves; abducens; osteomyelitis; methicillin-resistant Staphylococcus aureus;

D O I：

10.1016/j.ijporl.2008.02.025

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

A previously healthy 10-year-old patient with headache, otalgia, and hearing loss was diagnosed with pachymeningitis and methicillin-resistant Staphylococcus aureus otitis media and bacteremia. Despite antimicrobial therapy, intracranial extension progressed, including clival osteomyelitis, sphenoid sinusitis, cavernous sinus inflammation and cranial nerve palsies, until the sphenoid sinus was drained. This case exemplifies an aggressive MRSA intracranial. infection that advanced despite antibiotic therapy. (C) 2008 Elsevier Ireland Ltd. All rights reserved.

引用

页码：945 / 951

页数：7

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