Amyloid double trouble

被引：27

作者：

Hardy, J ^{[1
]}

机构：

[1] NIA, Neurogenet Lab, Bethesda, MD 20892 USA

来源：

NATURE GENETICS | 2006年 / 38卷 / 01期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1038/ng0106-11

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

A new study shows that some cases of early-onset Alzheimer disease result from duplications of the APP locus, which encodes the amyloid beta precursor protein. This finding fulfills a 20-year-old prediction that genetic variability in APP expression could lead to disease and provides further, perhaps definitive, evidence for the amyloid hypothesis of the disorder.

引用

页码：11 / 12

页数：3

共 15 条

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