Analysis of a new type of high pressure homogeniser. A study of the flow pattern

被引:200
作者
Floury, J
Bellettre, J
Legrand, J
Desrumaux, A
机构
[1] GEPEA, UMR 6144, CNRS, F-44322 Nantes, France
[2] Ecole Mines Nantes, DSEE, F-44307 Nantes, France
[3] Univ Nantes, CNRS, GEPEA, UMR 6144,IUT St Nazaire, F-44602 St Nazaire, France
关键词
homogenisation; hydrodynamics; numerical analysis; shear; turbulence; cavitation;
D O I
10.1016/j.ces.2003.11.017
中图分类号
TQ [化学工业];
学科分类号
0817 ;
摘要
High-pressure homogenisation is a key unit operation used to disrupt fat globules or cells containing intracellular bioproducts (AlChE J. 43(4) (1997) 1100). Modelling and optimisation of a small homogenising unit are often restrained by a lack of information on the flow conditions within the homogeniser valve. A numerical investigation of the flow within such a new homogenising valve, capable to reach pressure as high as 350 MPa (Stansted Fluid Power Ltd, UK) is presented. Results are obtained using the finite-volume technique and a RNG kappa-epsilon turbulence model with low Reynolds number near wall treatment conditions. An experimental measurement of the size of the valve gap is presented in order to validate mathematical relations that give valve gap sizes versus homogenising pressure. The modelling results give detailed information on the mechanical stresses and the high shear rates in small disruption valves, and also reveal other phenomena that could not be easily determined experimentally. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:843 / 853
页数:11
相关论文
共 21 条
  • [1] [Anonymous], 1980, SERIES COMPUTATIONAL, DOI [DOI 10.1201/9781482234213, 10.1201/9781482234213]
  • [2] BURGAUD I, 1990, INT J FOOD SCI TECH, V25, P39, DOI 10.1111/j.1365-2621.1990.tb01057.x
  • [3] FLOURY J, 2004, IN PRESS CHEM ENG SC
  • [4] *FLUENTS INC, 1998, FLUENT US GUID VERS
  • [5] Numerical and experimental study of a homogenizer impinging jet
    Kleinig, AR
    Middelberg, APJ
    [J]. AICHE JOURNAL, 1997, 43 (04) : 1100 - 1107
  • [6] The correlation of cell disruption with homogenizer valve pressure gradient determined by computational fluid dynamics
    Kleinig, AR
    Middelberg, APJ
    [J]. CHEMICAL ENGINEERING SCIENCE, 1996, 51 (23) : 5103 - 5110
  • [7] KLEINIG AR, 1995, CHEMECA 95, V3, P50
  • [8] Kumar PS, 1999, CHEM ENG TECHNOL, V22, P1017, DOI 10.1002/(SICI)1521-4125(199912)22:12<1017::AID-CEAT1017>3.0.CO
  • [9] 2-L
  • [10] Gaulin homogenization: A mechanistic study
    Lander, R
    Manger, W
    Scouloudis, M
    Ku, A
    Davis, C
    Lee, A
    [J]. BIOTECHNOLOGY PROGRESS, 2000, 16 (01) : 80 - 85