Magnetic resonance spectroscopy in multiple sclerosis: window into the diseased brain

被引：35

作者：

Wolinsky, JS

Narayana, PA

机构：

[1] Univ Texas, Hlth Sci Ctr, Dept Neurol, Houston, TX 77030 USA

[2] Univ Texas, Hlth Sci Ctr, Dept Radiol, Houston, TX USA

来源：

CURRENT OPINION IN NEUROLOGY | 2002年 / 15卷 / 03期

关键词：

D O I：

10.1097/00019052-200206000-00004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Magnetic resonance spectroscopy provides noninvasive insight into the regional and global biochemical alterations that are concomitants of the dynamic processes that underlie the evolution of fundamental pathologic changes in multiple sclerosis. These include now well-recognized alterations of neuronal biochemical markers that accompany tissue destruction readily visualized by magnetic resonance imaging, but also dynamic changes in several metabolites that indicate pathological processes that precede the magnetic resonance imaging-defined lesion, or completely escape current high-resolution imaging.

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页码：247 / 251

页数：5

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