Non conservation of the meiotic function of the Ski8/Rec103 homolog in Arabidopsis

被引：35

作者：

Jolivet, Sylvie ^{[1
]}

Vezon, Daniel ^{[1
]}

Froger, Nicole ^{[1
]}

Mercier, Raphael ^{[1
]}

机构：

[1] INRA, Stn Genet & Ameliorat Plantes, Inst Jean Pierre Bourgin, F-78026 Versailles, France

来源：

GENES TO CELLS | 2006年 / 11卷 / 06期

关键词：

D O I：

10.1111/j.1365-2443.2006.00972.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Meiotic recombination involves the formation and repair of DNA double-strand breaks (DSB). One of the genes required for DSB formation in the yeast Saccharomyces cerevisiae, Ski8/Rec103, is intriguing because it also plays a role in cytoplasmic RNA metabolism, a function difficult to relate to DSB formation. The meiotic role of Ski8 is conserved in several fungi, but has not been investigated outside this kingdom. We identified the Ski8 homolog in Arabidopsis thaliana and isolated two mutants. We showed that the Arabidopsis Ski8 homolog was required for normal plant development and growth, suggesting a conserved somatic function, but that it was not required for meiotic recombination or progression. The data presented here provide strong evidence that the meiotic role of Ski8 is not conserved in Arabidopsis and sequence analysis suggests that this may also be the case in a range of other species.

引用

页码：615 / 622

页数：8

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