The genetics and molecular structure of the Drosophila pair-rule gene odd Oz (odz)

被引：15

作者：

Levine, A ^{[1
]}

Gartenberg, D ^{[1
]}

Yakov, R ^{[1
]}

Lieberman, Y ^{[1
]}

BudaiHadrian, O ^{[1
]}

BashanAhrend, A ^{[1
]}

Wides, R ^{[1
]}

机构：

[1] BAR ILAN UNIV, DEPT LIFE SCI, IL-52900 RAMAT GAN, ISRAEL

来源：

GENE | 1997年 / 200卷 / 1-2期

关键词：

genomic sequence; segmentation gene; pattern formation; tyrosine kinase substrate;

D O I：

10.1016/S0378-1119(97)00375-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Null alleles of the odz pair-rule gene have been generated as small Deficiency chromosome mutations. The true null phenotype of odz in segmentation is now seen to be very similar to that originally characterized, with each odd segment removed. No other previously isolated mutations in the genomic region proved allelic to odz. The generated Deficiencies covering the odz locus and immediately surrounding regions do not cover any other gene tested from that region. The entire odz gene has been cloned and mapped, and represents more than 120 kb of genomic DNA. The gene has been sequenced, except for two very large introns. Analysis of the upstream control region of the gene indicates the presence of a large number of putative binding sites for transcription factors that direct relevant developmentally regulated gene transcription. (C) 1997 Elsevier Science B.V.

引用

页码：59 / 74

页数：16

共 37 条

[1]

AKAM M, 1987, DEVELOPMENT, V101, P1

[2]

ALTSCHUL SF, 1990, J MOL BIOL, V215, P403, DOI 10.1006/jmbi.1990.9999

[3] TEN(M), A DROSOPHILA GENE-RELATED TO TENASCIN, IS A NEW PAIR-RULE GENE [J].