Chemical constituents of Isatis indigotica

被引:122
作者
Wu, XY
Liu, YH
Sheng, WY
Sun, J
Qin, GW
机构
[1] CHINESE ACAD SCI, SHANGHAI INST MAT MED, SHANGHAI 200031, PEOPLES R CHINA
[2] TONGJI MED UNIV, TONGJI AFFILIATED HOSP, WUHAN 430030, PEOPLES R CHINA
[3] SHANGHAI INST PLANNED PARENTHOOD RES, SHANGHAI 200032, PEOPLES R CHINA
[4] CHINESE ACAD SCI, SHANGHAI INST ORGAN CHEM, SHANGHAI 200032, PEOPLES R CHINA
关键词
Isatis indigotica; Cruciferae; (E)-3-(3'; 5'-dimethoxy-4'-hydroxybenzylidene)-2-indolinone; antiendotoxic activity;
D O I
10.1055/s-2006-957604
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
From the roots of Isatis indigotica, ten compounds (1-10) were isolated. Compound 1 is a new alkaloid whose structure was elucidated as (E)-3-(3',5'-dimethoxy-4'-hydroxybenzylidene)-2-indolinone. Compounds 2-4 were discovered for the first time from a natural source and compounds 5-7 were originally isolated from this species. In a preliminary study, compounds 4-8 showed antiendotoxic activities in vitro.
引用
收藏
页码:55 / 57
页数:3
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