Three-dimensional domain duplication, swapping and stealing

被引：73

作者：

Heringa, J

Taylor, WR

机构：

[1] Division of Mathematical Biology, Natl. Inst. Med. Res., Ridgeway, M., London

来源：

CURRENT OPINION IN STRUCTURAL BIOLOGY | 1997年 / 7卷 / 03期

关键词：

D O I：

10.1016/S0959-440X(97)80060-7

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Examination of multidomain and/or multimeric protein structures can reveal evolutionary paths to a more complex 3D organization. Over the past few years, proteins have been shown to evolve while preserving mutual domain organization and interfaces. The recent advances in understanding domain reorganization and mobility highlight the versatility and efficiency of protein structural evolution. (C) Current Biology Ltd.

引用

收藏

页码：416 / 421

页数：6

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