Catalytic enantioselective reactions.: Part 16.: Oxazaborolidine-catalyzed asymmetric borane reduction of α-keto acetals

被引:29
作者
Cho, BT [1 ]
Chun, YS [1 ]
机构
[1] Hallym Univ, Dept Chem, Chunchon 200702, Kangwon Do, South Korea
来源
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1999年 / 15期
关键词
D O I
10.1039/a903335a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Asymmetric reductions of alpha-keto acetals using various oxazaborolidines and borane reagents as catalyst and the hydride source, respectively, were compared. The reduction catalyzed by Corey's CBS reagents with N-phenylamine-borane reagents provided alpha-hydroxy acetals with very high enantioselectivities for most aromatic analogues.
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页码:2095 / 2100
页数:6
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