Components for tethered bilayer membranes: Synthesis of hydrophilically substituted phytanol derivatives

被引：7

作者：

Burns, CJ ^{[1
]}

Field, LD ^{[1
]}

Morgan, J ^{[1
]}

Petteys, BJ ^{[1
]}

Prashar, J ^{[1
]}

Ridley, DD ^{[1
]}

Sandanayake, KRAS ^{[1
]}

Vignevich, V ^{[1
]}

机构：

[1] Univ Sydney, Sch Chem, Cooperat Res Ctr Mol Engn & Technol, Sydney, NSW 2006, Australia

来源：

AUSTRALIAN JOURNAL OF CHEMISTRY | 2001年 / 54卷 / 07期

关键词：

D O I：

10.1071/CH01111

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

In order to optimize the performance of the AMBRI(TM) biosensor (Nature 1997, 387, 580), a variety of hydrophilic linkers between the hydrophobic bilayer membrane and the gold surface have been synthesized. The principal components are prepared from phytanyl hemisuccinate, which is linked by repeating ethylene glycol or propylene glycol units to a second succinic acid unit. The syntheses of analogous substances in which the ester links are replaced by amide and by ether links are also described.

引用

页码：431 / 438

页数：8

共 27 条

[1]

Asakawa M, 1999, EUR J ORG CHEM, V1999, P985, DOI 10.1002/(SICI)1099-0690(199905)1999:5<985::AID-EJOC985>3.0.CO

[2]

2-O

[3] Solution- and solid-phase synthesis of components for tethered bilayer membranes [J].

Bendavid, A ;

Burns, CJ ;

Field, LD ;

Hashimoto, K ;

Ridley, DD ;

Sandanayake, KRAS ;

Wieczorek, L .

JOURNAL OF ORGANIC CHEMISTRY, 2001, 66 (11) :3709-3716

[4] ENANTIOSELECTIVE HYDROBORATION MEDIATED BY HOMOCHIRAL RHODIUM CATALYSTS [J].

BURGESS, K ;

OHLMEYER, MJ .

JOURNAL OF ORGANIC CHEMISTRY, 1988, 53 (21) :5178-5179

[5] A convenient synthetic route to differentially functionalized long chain polyethylene glycols [J].

Burns, CJ ;

Field, LD ;

Hashimoto, K ;

Petteys, BJ ;

Ridley, DD ;

Sandanayake, KRAS .

SYNTHETIC COMMUNICATIONS, 1999, 29 (13) :2337-2347

[6] Synthesis of stereoisomerically pure monoether lipids [J].

Burns, CJ ;

Field, LD ;

Hashimoto, K ;

Petteys, BJ ;

Ridley, DD ;

Rose, M .

AUSTRALIAN JOURNAL OF CHEMISTRY, 1999, 52 (05) :387-394

[7]

Burns CJ, 1999, AUST J CHEM, V52, P1071

[8] The AMBRI Biosensor - Stabilising artificial membranes and receptor attachment [J].

Burns, CJ ;

Braach-Maksvytis, VBL ;

King, LG ;

Osman, PDJ ;

Pace, RJ ;

Raguse, B ;

Wieczorek, L ;

Cornell, BA .

ADVANCED MATERIALS AND OPTICAL SYSTEMS FOR CHEMICAL AND BIOLOGICAL DETECTION, 1999, 3858 :17-24

[9] A 'litmus test' for molecular recognition using artificial membranes [J].

Charych, D ;

Cheng, Q ;

Reichert, A ;

Kuziemko, G ;

Stroh, M ;

Nagy, JO ;

Spevak, W ;

Stevens, RC .

CHEMISTRY & BIOLOGY, 1996, 3 (02) :113-120

[10] A biosensor that uses ion-channel switches [J].

Cornell, BA ;

BraachMaksvytis, VLB ;

King, LG ;

Osman, PDJ ;

Raguse, B ;

Wieczorek, L ;

Pace, RJ .

NATURE, 1997, 387 (6633) :580-583

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