Heck Cross-Coupling of Aryldiazonium Tetrafluoroborate with Acrylates Catalyzed by Palladium on Charcoal

被引：83

作者：

Felpin, Francois-Xavier ^{[1
]}

Fouquet, Eric ^{[1
]}

Zakri, Cecile ^{[2
]}

机构：

[1] Univ Bordeaux, CNRS, Inst Mol Sci, F-33405 Talence, France

[2] Univ Bordeaux, Ctr Rech Paul Pascal, CNRS, F-33600 Pessac, France

来源：

ADVANCED SYNTHESIS & CATALYSIS | 2008年 / 350卷 / 16期

关键词：

acrylates; aryldiazonium tetrafluoroborate salts; Heck reaction; palladium on charcoal; practical cross-coupling;

D O I：

10.1002/adsc.200800539

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A property-activity relationship study of various palladium supported on charcoal (Pd/C) catalysts has been undertaken for the Heck reaction of aryldiazonium tetrafluoroborate with acrylates. The optimized protocol enables the cross-coupling with a low loading of palladium at room temperature in technical grade methanol. Although the catalyst could not be recycled at this time, measurement of the palladium content by inductively coupled plasma mass spectrometry (ICP-MS) shows low palladium contamination of the solvent and product, rendering this method safer for the environment compared to homogeneous conditions.

引用

页码：2559 / 2565

页数：7

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