Diastereoselective protonation of chiral enolates derived from 2,4-dimethyl-1-tetralone using carbonyl chelating proton donors

被引：12

作者：

Eames, J ^{[1
]}

机构：

[1] Univ London Queen Mary & Westfield Coll, Dept Chem, London E1 4NS, England

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(99)01114-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of syn-2,4-dimethyl-1-tetralone 6 via a deprotonation-reprotonation strategy using chelating proton sources is discussed. We comment on the differences between direct protonation and deprotonation-reprotonation of chiral enolates in the presence of diisopropylamine and LiBr. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：5787 / 5790

页数：4

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