Immunohistochemical study of p185 HER2 and DF3 in primary breast cancer and correlation with CA-15-3 serum tumor marker

被引：3

作者：

Dimas, C

Frangos-Plemenos, M

Kouskouni, E

Kondis-Pafitis, A

机构：

[1] Areteion Hosp, Athens Med Sch, Dept Microbiol, Athens 11528, Greece

[2] Areteion Hosp, Athens Med Sch, Dept Pathol, Athens 11528, Greece

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER | 2002年 / 12卷 / 01期

关键词：

breast cancer; DF3; HER2; immunohistochemistry; p185; tumor marker;

D O I：

10.1046/j.1525-1438.2002.01073.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Human epidermal growth factor receptor 2 (p185 HER2) oncoprotein immunohistochemical expression and DF3 antigen distribution were evaluated in 129 patients with primary breast cancer. p185 HER2 overexpession was positively correlated with the degree of differentiation, metastatic disease, progesterone receptors, and cytoplasmic distribution of DF3 antigen. p185 HER2 overexpression had prognostic significance for the disease-free interval.

引用

页码：74 / 79

页数：6

共 38 条

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