National outcomes for the treatment of ruptured abdominal aortic aneurysm: Comparison of open versus endovascular repairs

被引:116
作者
Egorova, Natalia
Giacovelli, Jeannine
Greco, Giampaolo
Gelijns, Annetine
Kent, Craig K.
McKinsey, James F.
机构
[1] International Center for Innovation, Outcomes Research (InCHOIR) Columbia University, New York, NY
[2] New York-Presbyterian Hospital, The University Hospital of Columbia and Cornell, New York, NY
关键词
D O I
10.1016/j.jvs.2008.06.036
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: Endovascular repair (EVAR) of ruptured abdominal aortic aneurysms (rAAA) has been shown to acutely decrease procedural mortality compared to open aortic repair (OAR). However, little is known about the effect of choice of procedure; EVAR vs OAR, or the impact of physician and institution volume on long-term survival and outcome. Methods: Patients hospitalized with rAAA who underwent either OAR or EVAR, were derived from the Medicare inpatient dataset (1995-2004) using ICD9 codes. We evaluated long-term survival after OAR and EVAR in the entire fee-for-service Medicare population, and then in patients matched by propensity score to create two similar cohorts for comparison with Kaplan-Meier analysis. Annual surgeon and hospital volumes of EVAR (elective and ruptured), OAR (elective and ruptured), and rAAA (EVAR and OAR) were divided into quintiles to determine if increasing volumes correlate with decreasing mortality. Predictors of survival were determined by Cox modeling. Results: A total of 43,033 Medicare beneficiaries had rAAA repair: 41,969 had OAR and 1,064 had EVAR. The proportions of patients with diabetes, hypertension, cardiovascular, cerebrovascular, renal disease, hyperlipidemia, and cancer were statistically higher in the EVAR than in the OAR group, whereas lower extremity vascular disease was higher in the OAR group. The initial evaluation of EVAR vs OAF, prior to propensity matching, showed no statistical advantage in EVAR-survival after 90 days. The survival analysis of patients matched by propensity score showed a benefit of EVAR over OAR that persisted throughout the 4 years of follow-up (P = .0042). Perioperative and long-term survival after rAAA repair correlated with increasing annual surgeon and hospital volume in OAR and EVAR and also with rAAA experience. EVAR repair had a protective effect (HR = 0.8.57, P = .0061) on long-term survival controlling for comorbidities, demographics, and hospital and surgeon volume. Conclusion:When EVAR and OAR patients are compared using a reliable statistical technique such as propensity analysis, the perioperative survival advantage of rAAA repaired endovascularly is maintained over the long term. Institutional experience with rAAA is critical for survival after either OAR or EVAR. (J Vasc Surg 2008;48:1092-1100.)
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页码:1092 / 1100
页数:9
相关论文
共 32 条
[1]   The impact of endovascular treatment on in-hospital mortality following non-ruptured AAA repair over a decade: A population based study of 16,446 patients [J].
Akkersdijk, GJM ;
Prinssen, M ;
Blankensteijn, JD .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2004, 28 (01) :41-46
[2]   Emergency endovascular repair for ruptured abdominal aortic aneurysms: Feasibility and comparison of early results with conventional open repair [J].
Alsac, JM ;
Desgranges, P ;
Kobeiter, H ;
Becquemin, JP .
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY, 2005, 30 (06) :632-639
[3]   A statewide experience with endovascular abdominal aortic aneurysm repair: Rapid diffusion with excellent early results - Discussion [J].
Matsumura, JS ;
Anderson, PL ;
Muluk, SC ;
Green, RM ;
Dardik, A ;
Ricotta, JJ .
JOURNAL OF VASCULAR SURGERY, 2004, 39 (01) :18-19
[4]   Cardiac risk stratification in patients undergoing endoluminal graft repair of abdominal aortic aneurysm: A single-institution experience with 365 patients [J].
Aziz, IN ;
Lee, JT ;
Kopchok, GE ;
Donayre, CE ;
White, RA ;
de Virgilio, C .
JOURNAL OF VASCULAR SURGERY, 2003, 38 (01) :56-60
[5]   A meta-analysis of 50 years of ruptured abdominal aortic aneurysm repair [J].
Bown, MJ ;
Sutton, AJ ;
Bell, PRF ;
Sayers, RD .
BRITISH JOURNAL OF SURGERY, 2002, 89 (06) :714-730
[6]  
Burnand K, 2006, J VASC SURG, V43, P1121
[7]   Ruptured abdominal aortic aneurysm:: endovascular treatment [J].
Castelli, P ;
Caronno, R ;
Piffaretti, G ;
Tozzi, M ;
Laganà, D ;
Carrafiello, G ;
Cuffari, S ;
Bacuzzi, A .
ABDOMINAL IMAGING, 2005, 30 (03) :263-269
[8]   Cumulative sum failure analysis of the learning curve with endovascular abdominal aortic aneurysm repair [J].
Forbes, TL ;
DeRose, G ;
Kribs, SW ;
Harris, KA .
JOURNAL OF VASCULAR SURGERY, 2004, 39 (01) :102-108
[9]   Endovascular management of ruptured abdominal aortic aneurysms: 6-year experience from a Greek center [J].
Gerassimidis, TS ;
Papazoglou, KO ;
Kamparoudis, AG ;
Konstantinidis, KO ;
Karkos, CD ;
Karamanos, D ;
Sfyroeras, G .
JOURNAL OF VASCULAR SURGERY, 2005, 42 (04) :615-623
[10]  
Glasgow RE, 1996, WESTERN J MED, V165, P294