Brain stimulation improves associative memory in an individual with amnestic mild cognitive impairment

被引:83
作者
Cotelli, Maria [1 ]
Calabria, Marco [2 ]
Manenti, Rosa [1 ]
Rosini, Sandra [1 ]
Maioli, Claudio [3 ]
Zanetti, Orazio [1 ]
Miniussi, Carlo [1 ,3 ]
机构
[1] IRCCS Ctr San Giovanni di Dio Fatebenefratelli, I-25125 Brescia, Italy
[2] Univ Pompeu Fabra, Dept Technol, Barcelona, Spain
[3] Univ Brescia, Natl Neurosci Inst, Dept Biomed Sci & Biotechnol, Brescia, Italy
关键词
Neurorehabilitation; Parietal cortex; Face-name association; MCI; Brain stimulation; EPISODIC MEMORY; PARIETAL CORTEX; INTERFERENCE; RETRIEVAL;
D O I
10.1080/13554794.2011.588176
中图分类号
R74 [神经病学与精神病学];
学科分类号
100204 [神经病学];
摘要
In patients with cognitive deficits, brain stimulation has been shown to restore cognition (Miniussi et al., 2008, Brain Stimulation, 1, 326). The aim of this study was to assess whether repetitive Transcranial Magnetic Stimulation (rTMS) could improve memory performance in an individual with amnestic Mild Cognitive Impairment (aMCI). Stimulation of the left parietal cortex increased accuracy in an association memory task, and this improvement was still significant 24 weeks after stimulation began. These findings indicate that rTMS to the left parietal cortex improved memory performance in aMCI.
引用
收藏
页码:217 / 223
页数:7
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