What happens when Trypanosoma brucei leaves Africa

被引：38

作者：

Jensen, Robert E. ^{[2
]}

Simpson, Larry ^{[3
]}

Englund, Paul T. ^{[1
]}

机构：

[1] Johns Hopkins Med Sch, Dept Biol Chem, Baltimore, MD 21205 USA

[2] Johns Hopkins Med Sch, Dept Cell Biol, Baltimore, MD 21205 USA

[3] Univ Calif Los Angeles, Dept Microbiol Immunol & Mol Genet, Los Angeles, CA 90095 USA

来源：

TRENDS IN PARASITOLOGY | 2008年 / 24卷 / 10期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/j.pt.2008.06.007

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Julius Lukes and co-workers evaluated the evolutionary origin of Trypanosoma equiperdum and Trypanosoma evansi, parasites that cause horse and camel diseases. Although similar to T. brucei, the sleeping-sickness parasite, these trypanosomes do not cycle through the tsetse fly and have been able to spread beyond Africa. Transmission occurs sexually, or via blood-sucking flies or vampire bats. They concluded that these parasites, which resemble yeast petite mutants, are T. brucei sub-species, which have evolved recently through changes in mitochondrial DNA.

引用

页码：428 / 431

页数：4

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