Biological alternatives to insulin therapy

被引：5

作者：

Bretzel, RG ^{[1
]}

机构：

[1] Univ Giessen, Dept Med 3, Med Klin & Poliklin 3, D-35385 Giessen, Germany

来源：

EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES | 1999年 / 107卷

关键词：

pancreas transplantation; islet transplantation; end-stage renal disease; kidney transplantation; allo-autoimmunity; immunosuppression; immunotolerance;

D O I：

10.1055/s-0029-1212149

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Beta-cell replacement either by pancreas or islet transplantation is the only treatment to achieve an insulin-independent, constantly normoglycemic state avoiding hypoglycemic episodes in patients with type-1 diabetes mellitus. This article reviews the worldwide experience with these treatments and reports the very recent progress as well as the perspectives of islet transplants in non-uremic patients.

引用

页码：S39 / S43

页数：5

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