Evidence that Cryptococcus neoformans is melanized in pigeon excreta:: Implications for pathogenesis

被引:48
作者
Nosanchuk, JD
Rudolph, J
Rosas, AL
Casadevall, A
机构
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Med, Div Infect Dis, Bronx, NY 10461 USA
[2] Yeshiva Univ Albert Einstein Coll Med, Dept Microbiol & Immunol, Bronx, NY 10461 USA
关键词
D O I
10.1128/IAI.67.10.5477-5479.1999
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Structures similar to the melanin "ghosts" of melanized cryptococcal cells were isolated from pigeon excreta contaminated with Cryptococcus neoformans, and their growth in pigeon excreta supported melanization. The results suggest that environmental C. neoformans cells are melanized and imply that initial infection may involve exposure to melanized cells.
引用
收藏
页码:5477 / 5479
页数:3
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