Living-donor right hepatectomy with or without inclusion of middle hepatic vein: Comparison of morbidity and outcome in 56 patients

被引:67
作者
Cattral, MS [1 ]
Molinari, M
Vollmer, CM
McGilvray, I
Wei, A
Walsh, M
Adcock, L
Marks, N
Lilly, L
Girgrah, N
Levy, G
Greig, PD
Grant, DR
机构
[1] Univ Toronto, Toronto Gen Hosp, Univ Hlth Network, Dept Surg,Multiorgan Transplantat Program, Toronto, ON M5G 1L7, Canada
[2] Univ Toronto, Toronto Gen Hosp, Univ Hlth Network, Dept Med,Multiorgan Transplantat Program, Toronto, ON M5G 1L7, Canada
关键词
liver transplantation; living donor;
D O I
10.1111/j.1600-6143.2004.00405.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Venous congestion of segments V and VIII is observed frequently in living-donor right lobe liver transplants without middle hepatic vein (MHV) drainage, and can be a cause of graft dysfunction and failure. Inclusion of the MHV with the graft is controversial, however, because of the perceived potential for increased donor morbidity. We compared the outcome of living liver donors in whom the MHV was either left intact in the donor (group 1; n = 28) or was removed with the graft (group 2; n = 28). All prospective donors completed n extensive multidisciplinary evaluation to determine suitability for surgery and to ensure that the MHV could be removed safely without compromising venous outflow from the remaining liver. Patient demographics including age, weight, body-mass index, and liver volumetry as determined by computerized tomography were similar in both groups. Operative time in group 2 was significantly shorter than in group 1. There was no difference in estimated blood loss, transfusion requirements, peak serum liver tests, time interval from surgery to complete normalization of liver tests, complications, and length of hospitalization. We conclude that including the MHV with living-donor right lobe grafts can be performed safely in most donors.
引用
收藏
页码:751 / 757
页数:7
相关论文
共 27 条
[1]   Adult-to-adult living donor liver transplantation using right-lobe grafts: Results and lessons learned from a single-center experience [J].
Bak, T ;
Wachs, M ;
Trotter, J ;
Everson, G ;
Trouillot, T ;
Kugelmas, M ;
Steinberg, T ;
Kam, I .
LIVER TRANSPLANTATION, 2001, 7 (08) :680-686
[2]   Impact of hospital volume on operative mortality for major cancer surgery [J].
Begg, CB ;
Cramer, LD ;
Hoskins, WJ ;
Brennan, MF .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1998, 280 (20) :1747-1751
[3]   Critical graft size in adult-to-adult living donor liver transplantation: Impact of the recipient's disease [J].
Ben-Haim, M ;
Emre, S ;
Fishbein, TM ;
Sheiner, PA ;
Bodian, CA ;
Kim-Schluger, L ;
Schwartz, ME ;
Miller, CM .
LIVER TRANSPLANTATION, 2001, 7 (11) :948-953
[4]   Reconstruction of middle hepatic vein of a living-donor right lobe liver graft with recipient left portal vein [J].
Cattral, MS ;
Greig, PD ;
Muradali, D ;
Grant, D .
TRANSPLANTATION, 2001, 71 (12) :1864-1866
[5]   Hepatic resection in the United States - Indications, outcomes, and hospital procedural volumes from a nationally representative database [J].
Dimick, JB ;
Cowan, JA ;
Knol, JA ;
Upchurch, GR .
ARCHIVES OF SURGERY, 2003, 138 (02) :185-191
[6]   Functional analysis of grafts from living donors - Implications for the treatment of older recipients [J].
Emond, JC ;
Renz, JF ;
Ferrell, LD ;
Rosenthal, P ;
Lim, RC ;
Roberts, JP ;
Lake, JR ;
Ascher, NL .
ANNALS OF SURGERY, 1996, 224 (04) :544-552
[7]   Safety and necessity of including the middle hepatic vein in the right lobe graft in adult-to-adult live donor liver transplantation [J].
Fan, ST ;
Lo, CM ;
Liu, CL ;
Wang, WX ;
Wong, J .
ANNALS OF SURGERY, 2003, 238 (01) :137-148
[8]   Safety of donors in live donor liver transplantation using right lobe grafts [J].
Fan, ST ;
Lo, CM ;
Liu, CL ;
Yong, BH ;
Chan, JKF ;
Ng, IOL .
ARCHIVES OF SURGERY, 2000, 135 (03) :336-340
[9]   Technical refinement in adult-to-adult living donor liver transplantation using right lobe graft [J].
Fan, ST ;
Lo, CM ;
Liu, CL .
ANNALS OF SURGERY, 2000, 231 (01) :126-131
[10]   The relationship between hospital volume and outcomes of hepatic resection for hepatocellular carcinoma [J].
Glasgow, RE ;
Showstack, JA ;
Katz, PP ;
Corvera, CU ;
Warren, RS ;
Mulvihill, SJ .
ARCHIVES OF SURGERY, 1999, 134 (01) :30-35