Role of the Porphyromonas gingivalis InlJ protein in homotypic and heterotypic biofilm development

被引：47

作者：

Capestany, CA ^{[1
]}

Kuboniwa, M ^{[1
]}

Jung, IY ^{[1
]}

Park, Y ^{[1
]}

Tribble, GD ^{[1
]}

Lamont, RJ ^{[1
]}

机构：

[1] Univ Florida, Coll Dent, Dept Oral Biol, Gainesville, FL 32610 USA

来源：

INFECTION AND IMMUNITY | 2006年 / 74卷 / 05期

关键词：

D O I：

10.1128/IAI.74.5.3002-3005.2006

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The oral pathogen Porphyromonas gingivalis expresses a homolog of the internalin family protein InIJ. Inactivation of inlJ reduced monospecies biofilm formation by P. gingivalis. In contrast, heterotypic P. gingivalis-Streptococcus gordonii biofilm formation was enhanced in the InlJ-deficient mutant. The results indicate a nuanced role for InIJ in regulating biofilm accumulations of P. gingivalis.

引用

页码：3002 / 3005

页数：4

共 18 条

[1] Surface proteins and the pathogenic potential of Listeria monocytogenes
Cabanes, D
Dehoux, P
Dussurget, O
Frangeul, L
Cossart, P
[J]. TRENDS IN MICROBIOLOGY, 2002, 10 (05) : 238 - +
[2] Searching the Porphyromonas gingivalis genome with peptide fragmentation mass spectra
Chen, WB
Laidig, KE
Park, Y
Park, K
Yates, JR
Lamont, RJ
Hackett, M
[J]. ANALYST, 2001, 126 (01) : 52 - 57
[3] Invasion of mammalian cells by Listeria monocytogenes:: functional mimicry to subvert cellular functions
Cossart, P
Pizarro-Cerdá, J
Lecuit, M
[J]. TRENDS IN CELL BIOLOGY, 2003, 13 (01) : 23 - 31
[4] Statistical analysis of Pseudomonas aeruginosa biofilm development:: Impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression
Heydorn, A
Ersboll, B
Kato, J
Hentzer, M
Parsek, MR
Tolker-Nielsen, T
Givskov, M
Molin, S
[J]. APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2002, 68 (04) : 2008 - 2017
[5] Structural diversity of leucine-rich repeat proteins
Kajava, AV
[J]. JOURNAL OF MOLECULAR BIOLOGY, 1998, 277 (03) : 519 - 527
[6] Role of the Streptococcus gordonii SspB protein in the development of Porphyromonas gingivalis biofilms on streptococcal substrates
Lamont, RJ
El-Sabaeny, A
Park, Y
Cook, GS
Costerton, JW
Demuth, DR
[J]. MICROBIOLOGY-SGM, 2002, 148 : 1627 - 1636
[7] Identification of novel stage-specific genetic requirements through whole genome transcription profiling of Vibrio cholerae biofilm development
Moorthy, S
Watnick, PI
[J]. MOLECULAR MICROBIOLOGY, 2005, 57 (06) : 1623 - 1635
[8] Initiation of biofilm formation in Pseudomonas fluorescens WCS365 proceeds via multiple, convergent signalling pathways:: a genetic analysis
O'Toole, GA
Kolter, R
[J]. MOLECULAR MICROBIOLOGY, 1998, 28 (03) : 449 - 461
[9] Short fimbriae of Porphyromonas gingivalis and their role in coadhesion with Streptococcus gordonii
Park, Y
Simionato, MR
Sekiya, K
Murakami, Y
James, D
Chen, WB
Hackett, M
Yoshimura, F
Demuth, DR
Lamont, RJ
[J]. INFECTION AND IMMUNITY, 2005, 73 (07) : 3983 - 3989
[10] Identification of Porphyromonas gingivalis genes specifically expressed in human gingival epithelial cells by using differential display reverse transcription-PCR
Park, Y
Yilmaz, Ö
Jung, IY
Lamont, RJ
[J]. INFECTION AND IMMUNITY, 2004, 72 (07) : 3752 - 3758

← 1 2 →