Visualization of denervated muscle by gadolinium-enhanced MRI

被引：51

作者：

Bendszus, M

Koltzenburg, M

机构：

[1] Univ Wurzburg, Dept Neuroradiol, D-97080 Wurzburg, Germany

[2] Univ Wurzburg, Dept Neurol, D-8700 Wurzburg, Germany

来源：

NEUROLOGY | 2001年 / 57卷 / 09期

关键词：

D O I：

10.1212/WNL.57.9.1709

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Thirty patients presenting with foot drop due to lesions of the peroneal nerve or L5 spinal root were investigated with gadolinium (Gd)enhanced MRI of the lower leg. Significant enhancement was only seen in the denervated muscles in a pattern appropriate for the distribution of the nerve or root. In a rat model, identical changes in the denervated muscle were reproduced and seen as early as 24 hours after sciatic nerve transection. Thus, Gd-enhanced MRI is a new and sensitive technique to visualize denervated muscle.

引用

收藏

页码：1709 / 1711

页数：3

相关论文

共 10 条

[1] FIBRILLATORY ACTIVITY AND OTHER MEMBRANE-CHANGES IN PARTIALLY DENERVATED MUSCLES [J].

ARANCIO, O ;

CANGIANO, A ;

DEGRANDIS, D .

MUSCLE & NERVE, 1989, 12 (02) :149-153

[2] BLOOD-FLOW, MITOCHONDRIA, AND PERFORMANCE IN SKELETAL-MUSCLE AFTER DENERVATION AND REINNERVATION [J].

EISENBERG, HA ;

HOOD, DA .

JOURNAL OF APPLIED PHYSIOLOGY, 1994, 76 (02) :859-866

[3] DENERVATED HUMAN SKELETAL-MUSCLE - MR IMAGING EVALUATION [J].

FLECKENSTEIN, JL ;

WATUMULL, D ;

CONNER, KE ;

EZAKI, M ;

GREENLEE, RG ;

BRYAN, WW ;

CHASON, DP ;

PARKEY, RW ;

PESHOCK, RM ;

PURDY, PD .

RADIOLOGY, 1993, 187 (01) :213-218

[4] Effect of peripheral nerve injury on nuclear magnetic resonance relaxation times of rat skeletal muscle [J].

Hayashi, Y ;

Ikata, T ;

Takai, H ;

Takata, S ;

Ishikawa, M ;

Sogabe, T ;

Koga, K .

INVESTIGATIVE RADIOLOGY, 1997, 32 (03) :135-139

[5]

HUDLICKA O, 1968, Microvascular Research, V1, P147, DOI 10.1016/0026-2862(68)90014-9

[6] HISTOLOGIC BASIS FOR INCREASED EXTRAOCULAR-MUSCLE ENHANCEMENT IN GADOLINIUM-ENHANCED MR IMAGING [J].

KAISSAR, G ;

KIM, JH ;

BRAVO, S ;

SZE, G .

RADIOLOGY, 1991, 179 (02) :541-542

[7] Changes of sonographic, magnetic resonance tomographic, electromyographic, and histopathologic findings within a 2-month period of examinations after experimental muscle denervation [J].

Kullmer, K ;

Sievers, KW ;

Reimers, CD ;

Rompe, JD ;

Muller-Felber, W ;

Nagele, M ;

Harland, U .

ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY, 1998, 117 (4-5) :228-234

[8] MAGNETIC-RESONANCE IMAGING OF SKELETAL-MUSCLE - PROLONGATION OF T1 AND T2 SUBSEQUENT TO DENERVATION [J].

POLAK, JF ;

JOLESZ, FA ;

ADAMS, DF .

INVESTIGATIVE RADIOLOGY, 1988, 23 (05) :365-369

[9] DENERVATED SKELETAL-MUSCLE - MR-IMAGING - WORK-IN-PROGRESS [J].

UETANI, M ;

HAYASHI, K ;

MATSUNAGA, N ;

IMAMURA, K ;

ITO, N .

RADIOLOGY, 1993, 189 (02) :511-515

[10]

WEINMANN HJ, 1984, PHYSIOL CHEM PHYS ME, V16, P167