Indium-mediated mild and facile method for the synthesis of amides

被引：28

作者：

Cho, DH

Jang, DO ^{[1
]}

机构：

[1] Yonsei Univ, Dept Chem, Wonju 220710, South Korea

[2] Yonsei Univ, Ctr Bioact Mol Hybrids, Seoul 120749, South Korea

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 11期

关键词：

amides; indium; peptides;

D O I：

10.1016/j.tetlet.2004.01.114

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Indium-mediated coupling reactions of acyl chlorides and amines for the synthesis of amide bonds are described. The reaction afforded high yields of the desired amides under mild and neutral conditions, and it was applicable also to the preparation of peptides without epimerization. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：2285 / 2287

页数：3

共 27 条

[1]

ARENDT A, 1978, TETRAHEDRON LETT, P2711

[2]

Benz G, 1991, COMPREHENSIVE ORGANI, V6, P381

[3] RACEMIZATION IN PEPTIDE SYNTHESIS . MECHANISM-SPECIFIC MODELS [J].