学术探索
学术期刊
新闻热点
数据分析
智能评审

Antifungal mechanism of FK463 against Candida albicans and Aspergillus fumigatus

被引：62
作者：
Hatano, K [1 ]
Morishita, Y [1 ]
Nakai, T [1 ]
Ikeda, F [1 ]
机构：
[1] Fujisawa Pharmaceut Co Ltd, Med Biol Res Labs, Yodogawa Ku, Osaka 5328514, Japan
来源：
JOURNAL OF ANTIBIOTICS | 2002年 / 55卷 / 02期
关键词：
D O I：
10.7164/antibiotics.55.219
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
[No abstract available]
引用
收藏
页码：219 / 222
页数：4
相关论文
共 13 条
  • [1] CHARACTERIZATION AND CILOFUNGIN INHIBITION OF SOLUBILIZED ASPERGILLUS-FUMIGATUS (1,3)-BETA-D-GLUCAN SYNTHASE
    BEAULIEU, D
    TANG, J
    YAN, SB
    VESSELS, JM
    RADDING, JA
    PARR, TR
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (05) : 937 - 944
  • [2] Identification of the FKS1 gene of Candida albicans as the essential target of 1,3-beta-D-glucan synthase inhibitors
    Douglas, CM
    DIppolito, JA
    Shei, GJ
    Meinz, M
    Onishi, J
    Marrinan, JA
    Li, W
    Abruzzo, GK
    Flattery, A
    Bartizal, K
    Mitchell, A
    Kurtz, MB
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (11) : 2471 - 2479
  • [3] THE SACCHAROMYCES-CEREVISIAE FKS1 (ETG1) GENE ENCODES AN INTEGRAL MEMBRANE-PROTEIN WHICH IS A SUBUNIT OF 1,3-BETA-D-GLUCAN SYNTHASE
    DOUGLAS, CM
    FOOR, F
    MARRINAN, JA
    MORIN, N
    NIELSEN, JB
    DAHL, AM
    MAZUR, P
    BAGINSKY, W
    LI, WL
    ELSHERBEINI, M
    CLEMAS, JA
    MANDALA, SM
    FROMMER, BR
    KURTZ, MB
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1994, 91 (26) : 12907 - 12911
  • [4] Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of disseminated candidiasis and aspergillosis
    Ikeda, F
    Wakai, Y
    Matsumoto, S
    Maki, K
    Watabe, E
    Tawara, S
    Goto, T
    Watanabe, Y
    Matsumoto, F
    Kuwahara, S
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (03) : 614 - 618
  • [5] Cloning of the RHO1 gene from Candida albicans and its regulation of beta-1,3-glucan synthesis
    Kondoh, O
    Tachibana, Y
    Ohya, Y
    Arisawa, M
    Watanabe, T
    [J]. JOURNAL OF BACTERIOLOGY, 1997, 179 (24) : 7734 - 7741
  • [6] MORPHOLOGICAL EFFECTS OF LIPOPEPTIDES AGAINST ASPERGILLUS-FUMIGATUS CORRELATE WITH ACTIVITIES AGAINST (1,3)-BETA-D-GLUCAN SYNTHASE
    KURTZ, MB
    HEATH, IB
    MARRINAN, J
    DREIKORN, S
    ONISHI, J
    DOUGLAS, C
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (07) : 1480 - 1489
  • [7] Efficacy of FK463, a new lipopeptide antifungal agent, in mouse models of pulmonary aspergillosis
    Matsumoto, S
    Wakai, Y
    Nakai, T
    Hatano, K
    Ushitani, T
    Ikeda, F
    Tawara, S
    Goto, T
    Matsumoto, F
    Kuwahara, H
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2000, 44 (03) : 619 - 621
  • [8] In vitro activity of 1,3-beta-D-glucan synthase requires the GTP-binding protein Rho1
    Mazur, P
    Baginsky, W
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (24) : 14604 - 14609
  • [9] Cloning of the Candida albicans homolog of Saccharomyces cerevisiae GSC1/FKS1 and its involvement in beta-1,3-glucan synthesis
    Mio, T
    AdachiShimizu, M
    Tachibana, Y
    Tabuchi, H
    Inoue, SB
    Yabe, T
    YamadaOkabe, T
    Arisawa, M
    Watanabe, T
    YamadaOkabe, H
    [J]. JOURNAL OF BACTERIOLOGY, 1997, 179 (13) : 4096 - 4105
  • [10] CILOFUNGIN (LY121019) INHIBITS CANDIDA-ALBICANS (1-3)-BETA-D-GLUCAN SYNTHASE ACTIVITY
    TAFT, CS
    STARK, T
    SELITRENNIKOFF, CP
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1988, 32 (12) : 1901 - 1903
12