Magnetic nanoparticles applied in electrochemical detection of controllable DNA hybridization

被引：48

作者：

Zhu, XL

Han, K

Li, GX ^{[1
]}

机构：

[1] Nanjing Univ, Dept Biochem, Nanjing 210093, Peoples R China

[2] Nanjing Univ, Natl Key Lab Pharmaceut Biotechnol, Nanjing 210093, Peoples R China

来源：

ANALYTICAL CHEMISTRY | 2006年 / 78卷 / 07期

关键词：

D O I：

10.1021/ac051962x

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Electrochemical detection of hybridized DNA strands was achieved with a magnetic nanoparticle modified electrode and the commonly used electrochemical couple K-3[Fe(CN)(6)]/K-4[Fe(CN)(6)]. The detection proved to be fast and very simple. Further-more, magnetic nanoparticles could be employed to control the DNA hybridization process. An inhibited or an enhanced degree of hybridizing could be produced.

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页码：2447 / 2449

页数：3

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