Escherichia coli mutator genes

被引：140

作者：

Horst, JP ^{[1
]}

Wu, TH ^{[1
]}

Marinus, MG ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Mol Pharmacol & Toxicol, Worcester, MA 01655 USA

来源：

TRENDS IN MICROBIOLOGY | 1999年 / 7卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0966-842X(98)01424-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The isolation and characterization of Escherichia coli mutator genes have led to a better understanding of DNA replication fidelity mechanisms and to the discovery of important DNA repair pathways and their relationship to spontaneous mutagenesis. Mutator strains in a population of cells can be beneficial in that they allow rapid selection of variants during periods of stress, such as drug exposure.

引用

页码：29 / 36

页数：8

共 40 条

[1] Dominant negative mutator mutations in the mutL gene of Escherichia coli
Aronshtam, A
Marinus, MG
[J]. NUCLEIC ACIDS RESEARCH, 1996, 24 (13) : 2498 - 2504
[2] Transcription-induced mutations: Increase in C to T mutations in the nontranscribed strand during transcription in Escherichia coli
Beletskii, A
Bhagwat, AS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1996, 93 (24) : 13919 - 13924
[3] CARRAWAY M, 1987, GENETICS, V116, P343
[4] DOENIER RC, 1996, ESCHERICHIA COLI SAL
[5] Overexpression of vsr in Escherichia coli is mutagenic
Doiron, KMJ
Viau, S
Koutroumanis, M
Cupples, CG
[J]. JOURNAL OF BACTERIOLOGY, 1996, 178 (14) : 4294 - 4296
[6] OXYGEN-DEPENDENT MUTAGENESIS IN ESCHERICHIA-COLI LACKING SUPEROXIDE-DISMUTASE
FARR, SB
DARI, R
TOUATI, D
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) : 8268 - 8272
[7] Genetic requirements and mutational specificity of the Escherichia coli SOS mutator activity
Fijalkowska, IJ
Dunn, RL
Schaaper, RM
[J]. JOURNAL OF BACTERIOLOGY, 1997, 179 (23) : 7435 - 7445
[8] Foster PL, 1996, GENETICS, V142, P25
[9] LEVELS OF EPSILON, AN ESSENTIAL REPLICATION SUBUNIT OF ESCHERICHIA-COLI DNA POLYMERASE-III, ARE CONTROLLED BY HEAT-SHOCK PROTEINS
FOSTER, PL
MARINUS, MG
[J]. JOURNAL OF BACTERIOLOGY, 1992, 174 (23) : 7509 - 7516
[10] Fowler RG, 1997, FEMS MICROBIOL REV, V21, P43, DOI 10.1111/j.1574-6976.1997.tb00344.x

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