Cytokine signaling in sepsis: Redundancy, crosstalk, and regulatory mechanisms

被引：4

作者：

Cooney, RN ^{[1
]}

Yumet, G ^{[1
]}

机构：

[1] Penn State Univ, Milton S Hershey Med Ctr, Coll Med, Hershey, PA 17033 USA

来源：

CRITICAL CARE MEDICINE | 2002年 / 30卷 / 01期

关键词：

cytokine signaling; endotoxin; janus kinases; signal transducers and activators of transcription; interleukin-6;

D O I：

10.1097/00003246-200201000-00048

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

引用

页码：262 / 263

页数：2

共 17 条

[1]

Abraham E, 1998, LANCET, V351, P929

[2] Prevention of skeletal muscle catabolism in sepsis does not impair visceral protein metabolism [J].

Cooney, RN ;

Owens, E ;

Slaymaker, D ;

Vary, TC .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1996, 270 (04) :E621-E626

[3] Effects of tumor necrosis factor-binding protein on hepatic protein synthesis during chronic sepsis [J].

Cooney, RN ;

Kimball, SR ;

Maish, G ;

Shumate, M ;

Vary, TC .

JOURNAL OF SURGICAL RESEARCH, 2000, 93 (02) :257-264

[4] A new protein containing an SH2 domain that inhibits JAK kinases [J].

Endo, TA ;

Masuhara, M ;

Yokouchi, M ;

Suzuki, R ;

Sakamoto, H ;

Mitsui, K ;

Matsumoto, A ;

Tanimura, S ;

Ohtsubo, M ;

Misawa, H ;

Miyazaki, T ;

Leonor, N ;

Taniguchi, T ;

Fujita, T ;

Kanakura, Y ;

Komiya, S ;

Yoshimura, A .

NATURE, 1997, 387 (6636) :921-924

[5] RECOMBINANT HUMAN INTERLEUKIN-1 RECEPTOR ANTAGONIST IN THE TREATMENT OF PATIENTS WITH SEPSIS SYNDROME - RESULTS FROM A RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL [J].

FISHER, CJ ;

DHAINAUT, JFA ;

OPAL, SM ;

PRIBBLE, JP ;

BALK, RA ;

SLOTMAN, GJ ;

IBERTI, TJ ;

RACKOW, EC ;

SHAPIRO, MJ ;

GREENMAN, RL ;

REINES, HD ;

SHELLY, MP ;

THOMPSON, BW ;

LABRECQUE, JF ;

CATALANO, MA ;

KNAUS, WA ;

SADOFF, JC ;

ASTIZ, M ;

CARPATI, C ;

BONE, RC ;

FREIDMAN, B ;

MURE, AJ ;

BRATHWAITE, C ;

SHAPIRO, E ;

MELHORN, L ;

TAYLOR, R ;

KEEGAN, M ;

OBRIEN, J ;

SCHEIN, R ;

PENA, M ;

WASSERLOUF, M ;

OROPELLO, J ;

BENJAMIN, E ;

DELGUIDICE, R ;

EMMANUEL, G ;

LIE, T ;

ANDERSON, L ;

MARSHALL, J ;

DEMAJO, W ;

ROTSTEIN, O ;

FOSTER, D ;

ABRAHAM, E ;

MIDDLETON, H ;

PERRY, C ;

LEVY, H ;

FRY, DE ;

SIMPSON, SQ ;

CROWELL, RE ;

NEIDHART, M ;

STEVENS, D .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1994, 271 (23) :1836-1843

[6] Mechanisms of disease: Acute-phase proteins and other systemic responses to inflammation [J].

Gabay, C ;

Kushner, I .

NEW ENGLAND JOURNAL OF MEDICINE, 1999, 340 (06) :448-454

[7] Biologic control of injury and inflammation: Much more than too little or too late [J].

Guirao, X ;

Lowry, SF .

WORLD JOURNAL OF SURGERY, 1996, 20 (04) :437-446

[8] IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis [J].

Lang, CH ;

Fan, J ;

Cooney, R ;

Vary, TC .

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 1996, 270 (03) :E430-E437

[9] Inhibition of interleukin-6-activated janus kinases/signal transducers and activators of transcription but not mitogen-activated protein kinase signaling in liver of endotoxin-treated rats [J].

Ling, PR ;

Smith, RJ ;

Mueller, C ;

Mao, YL ;

Bistrian, BR .

CRITICAL CARE MEDICINE, 2002, 30 (01) :202-211

[10] Endotoxin-induced inhibition of growth hormone receptor signaling in rat liver in vivo [J].

Mao, YL ;

Ling, PR ;

Fitzgibbons, TP ;

McCowen, KC ;

Frick, GP ;

Bistrian, BR ;

Smith, RJ .

ENDOCRINOLOGY, 1999, 140 (12) :5505-5515

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