Genome structure of Ebola virus subtype Reston: differences among Ebola subtypes

被引：31

作者：

Ikegami, T

Calaor, AB

Miranda, ME

Niikura, M

Saijo, M

Kurane, I

Yoshikawa, Y

Morikawa, S

机构：

[1] Natl Inst Infect Dis, Dept Virol 1, Special Pathogens Lab, Tokyo 2080011, Japan

[2] Univ Tokyo, Grad Sch Agr & Life Sci, Dept Biomed Sci, Tokyo 1130033, Japan

[3] Res Inst Trop Med, Vet Res Dept, Muntinlupa, Philippines

来源：

ARCHIVES OF VIROLOGY | 2001年 / 146卷 / 10期

关键词：

D O I：

10.1007/s007050170049

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We determined the complete genome sequence of Ebola virus subtype Reston (EBO-R) in the Philippines in 1996. The deduced transcriptional signals were highly conserved among Ebola viruses except for the stop signal of L genes. The intergenic regions were composed of 4 to 7 nucleotides, and of 2 characteristic overlaps and a long intergenic region. The glycoprotein (GP) had several amino acid differences from EBO-R isolated in 1989 and 1992. The variety of GP sequences strongly suggests the independent introduction of EBO-R from unknown natural reservoirs in 1996.

引用

页码：2021 / 2027

页数：7

共 19 条

[1] THE COMPLETE NUCLEOTIDE-SEQUENCE OF THE POPP (1967) STRAIN OF MARBURG-VIRUS - A COMPARISON WITH THE MUSOKE (1980) STRAIN [J].