A novel imidazol-2-ylidene as a ligand for palladium-catalyzed synthesis of oxyindoles from o-haloanilides

被引：51

作者：

Zhang, TY ^{[1
]}

Zhang, HB ^{[1
]}

机构：

[1] Lilly Corp Ctr, Lilly Res Labs, Chem Proc Res & Dev, Indianapolis, IN 46285 USA

来源：

TETRAHEDRON LETTERS | 2002年 / 43卷 / 02期

关键词：

catalysis; catalyst; oxindole; indole; palladium; imidazolylidene;

D O I：

10.1016/S0040-4039(01)02138-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Oxyindoles were formed in good yields from 2-bromo- or chloroanilide in the presence of a base and a novel palladium imidazol-2-ylidene complex, through a process of metal-catalyzed intramolecular arylation of amide enolates. A wide range of substrates, including electron rich aryl chlorides, were found actives under the catalysis of this non-phosphinic, easily prepared ligand-metal system. (C) 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：193 / 195

页数：3

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