Synthesis of 4-substituted methyl 3-(2,3-epoxy)propoxythiophene-2-carboxylates

被引：6

作者：

Lissavetzky, J

Manzanares, I

机构：

[1] Inst. de Quím. Médica, E-28006 Madrid, Juan de la Cierva

来源：

HETEROCYCLES | 1996年 / 43卷 / 04期

关键词：

D O I：

10.3987/COM-95-7324

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of 4-substituted methyl 3-hydroxythiophene-2-carboxylates is reported. The selective O-alkylation by two methods of these compounds gives the correspondent epoxy derivatives.

引用

页码：775 / 780

页数：6

共 19 条

[1]

BOURVE H, 1969, THESIS U ERLANGEN

[2]

BRELIVET J, 1971, B SOC CHIM FR, P1344

[3] ANALOGS OF PROPRANOLOL - SYNTHESIS OF 3-ALKYLAMINO-1-(3-BENZO[B]THIENYLOXY)-2-PROPANOLS [J].

CONDE, S ;

CORRAL, C ;

LISSAVETZKY, J .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1980, 17 (05) :937-940

[4]

CONDE S, 1983, ARCH PHARM, V317, P537

[5] EFFECTS OF SUBSTITUENTS ON THE CHLORINATION OF METHYL 3-HYDROXYTHIOPHENE-2-CARBOXYLATE AND ON THE REACTION OF THE RESULTING CHLORINATED PRODUCTS WITH ACTIVE HYDROGEN CONTAINING COMPOUNDS [J].

CORRAL, C ;

LISSAVETZKY, J ;

MANZANARES, I .

JOURNAL OF HETEROCYCLIC CHEMISTRY, 1990, 27 (02) :315-319

[6]

CORRAL C, 1984, SYNTHESIS-STUTTGART, P847

[7]

CORRAL C, 1986, J CHEM RES-S, P168

[8]

DONOSO R, 1992, SYNTHESIS-STUTTGART, P526

[9]

GRONOWITZ S, 1985, THIOPHENE ITS DERI 1, P91

[10]

GRONOWITZ S, 1986, THIOPHENE ITS DERIVA, P1

← 1 2 →