Unearthing uric acid: An ancient factor with recently found significance in renal and cardiovascular disease

被引：137

作者：

Nakagawa, T.

Kang, D-H

Feig, D.

Sanchez-Lozada, L. G.

Srinivas, T. R.

Sautin, Y.

Ejaz, A. A.

Segal, M.

Johnson, R. J.

机构：

[1] Univ Florida, Div Nephrol Hypertens & Renal Transplantat, Gainesville, FL 32610 USA

[2] Ewha Womans Univ, Dept Med, Seoul 120750, South Korea

[3] Baylor Coll Med, Div Nephrol, Dept Med, Houston, TX 77030 USA

[4] Inst Nacl Cardiol Ignacio Chavez, Dept Nephrol, Mexico City, DF, Mexico

来源：

KIDNEY INTERNATIONAL | 2006年 / 69卷 / 10期

关键词：

hypertension; arteriolosclerosis; metabolic syndrome; chronic kidney disease; transplant-associated kidney disease;

D O I：

10.1038/sj.ki.5000391

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Uric acid is strongly associated with cardiovascular and renal disease, but is usually not considered to have a causal role. However, recent experimental, epidemiological, and clinical studies provocatively suggest that uric acid may contribute to the development of hypertension, metabolic syndrome, and kidney disease in some patients. Clinical studies are urgently needed to examine this important possibility.

引用

收藏

页码：1722 / 1725

页数：4

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