Study of metal and acid catalysed deprotection of propargyl ethers of alcohols via their allenyl ethers

被引：50

作者：

Mereyala, HB ^{[1
]}

Gurrala, SR ^{[1
]}

Mohan, SK ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Div Organ Chem 3, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON | 1999年 / 55卷 / 37期

关键词：

alcohols; isomerisation; enol ethers; OsO4;

D O I：

10.1016/S0040-4020(99)00631-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new method for the deprotection of prop-2-ynyl ethers 1b-9b is described. Isomerisation of 1b-9b to O-allenyl ethers 1d-9d and deprotection by reaction with Hg(OCOCF3)(2), aq.HCl, aq.CF3CO2H and best by use of a catalytic amount of OsO4 is described to obtain the alcohols 1a-9a in good yield. Application of this method for the deprotection of prop-2-enyl ethers 7c,8c,10c-13c via their corresponding prop-1-enyl ethers 7e,8e,10e-13e to obtain the corresponding alcohols 7a,8a,10a-13a is also described, (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：11331 / 11342

页数：12

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