Enzymatic formation of isochamigrene, a novel sesquiterpene, by alteration of the aspartate-rich region of trichodiene synthase

被引：29

作者：

Cane, DE ^{[1
]}

Xue, Q ^{[1
]}

VanEpp, JE ^{[1
]}

机构：

[1] CONCORDIA UNIV,DEPT CHEM & BIOCHEM,MONTREAL,PQ H3G 1M8,CANADA

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1996年 / 118卷 / 35期

关键词：

D O I：

10.1021/ja961897w

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：8499 / 8500

页数：2

共 27 条

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[2] BACK K, 1996, P NATL ACAD SCI USA, V93, P6741
[3] TRICHODIENE SYNTHASE - STEREOCHEMICAL STUDIES OF THE CRYPTIC ALLYLIC DIPHOSPHATE ISOMERASE ACTIVITY USING AN ANOMALOUS SUBSTRATE
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[4] TRICHODIENE BIOSYNTHESIS AND THE ENZYMATIC CYCLIZATION OF FARNESYL PYROPHOSPHATE
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[5] ISOPRENOID BIOSYNTHESIS - STEREOCHEMISTRY OF THE CYCLIZATION OF ALLYLIC PYROPHOSPHATES
CANE, DE
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1985, 18 (07) : 220 - 226
[6] Trichodiene synthase. Enzymatic formation of multiple sesquiterpenes by alteration of the cyclase active site
Cane, DE
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[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1996, 118 (06) : 1563 - 1564
[7] TRICHODIENE SYNTHASE - SYNERGISTIC INHIBITION BY INORGANIC PYROPHOSPHATE AND AZA ANALOGS OF THE BISABOLYL CATION
CANE, DE
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COATES, RM
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HOHN, TM
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (12) : 3454 - 3462
[8] TRICHODIENE SYNTHASE - SUBSTRATE-SPECIFICITY AND INHIBITION
CANE, DE
YANG, GH
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SHIM, JH
[J]. BIOCHEMISTRY, 1995, 34 (08) : 2471 - 2479
[9] OVERPRODUCTION OF SOLUBLE TRICHODIENE SYNTHASE FROM FUSARIUM-SPOROTRICHIOIDES IN ESCHERICHIA-COLI
CANE, DE
ZHEN, W
OLIVER, JS
HOHN, TM
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1993, 300 (01) : 416 - 422
[10] TRICHODIENE BIOSYNTHESIS AND THE STEREOCHEMISTRY OF THE ENZYMATIC CYCLIZATION OF FARNESYL PYROPHOSPHATE
CANE, DE
HA, HJ
PARGELLIS, C
WALDMEIER, F
SWANSON, S
MURTHY, PPN
[J]. BIOORGANIC CHEMISTRY, 1985, 13 (03) : 246 - 265

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