Population structure in the Mediterranean basin:: A Y chromosome perspective

被引：54

作者：

Capelli, C

Redhead, N

Romano, V

Calì, F

Lefranc, G

Delague, V

Megarbane, A

Felice, AE

Pascali, VL

Neophytou, PI

Poulli, Z

Novelletto, A

Malaspina, P

Terrenato, L

Berebbi, A

Fellous, M

Thomas, MG

Goldstein, DB

机构：

[1] UCL, Dept Biol, London, England

[2] Univ Cattolica Sacro Cuore, Ist Med Legale, Rome, Italy

[3] Univ Palermo, Dept Biopathol & Biomed Methodol, Palermo, Italy

[4] Oasi Inst Res Mental Retardat & Brain Aging IRCCS, Troina, Italy

[5] Univ Montpellier 2, Montpellier, France

[6] CNRS, UPR 1142, Inst Genet Humaine, Montpellier, France

[7] Univ St Joseph, Fac Med, Unite Genet Med, Beirut, Lebanon

[8] Univ Malta, Dept Pathol, Mol Genet Lab, Msida, Malta

[9] Mendel Ctr Biomed Sci, Nicosia, Cyprus

[10] Cyprus Res Ctr KYKEM, Nicosia, Cyprus

[11] Univ Calabria, Dept Cell Biol, I-87036 Arcavacata Di Rende, Italy

[12] Univ Roma Tor Vergata, Dept Biol, I-00173 Rome, Italy

[13] Kaplan Med Ctr, Inst Hematol, Rehovot, Israel

[14] Univ Paris, Dept Human Genet, F-75252 Paris, France

来源：

ANNALS OF HUMAN GENETICS | 2006年 / 70卷

关键词：

Mediterranean; Y chromosome; population genetic structure; STRs; UEPs;

D O I：

10.1111/j.1529-8817.2005.00224.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The Mediterranean region has been characterised by a number of pre-historical and historical demographic events whose legacy oil the current genetic landscape is still a matter of debate. In order to investigate the degree of population structure across the Mediterranean, we have investigated Y chromosome variation in I large dataset of Mediterranean populations, 11 of which are first described here. Our analyses identify four main clusters In the Mediterranean that can be labelled as North Africa, Arab, Central-East and West Mediterranean. Ill particular, Near Eastern samples tend to separate according to the presence of Arab Y chromosome lineages, suggesting that the Arab expansion played a major role in shaping the current genetic structuring within the Fertile Crescent.

引用

页码：207 / 225

页数：19

共 64 条

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