Dynamic combinatorial libraries of pseudo-peptide hydrazone macrocycles

被引：110

作者：

Cousins, GRL ^{[1
]}

Poulsen, SA ^{[1
]}

Sanders, JKM ^{[1
]}

机构：

[1] Univ Cambridge, Cambridge Ctr Mol Recognit, Chem Lab, Cambridge CB2 1EW, England

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 16期

关键词：

D O I：

10.1039/a904091i

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Combinatorial libraries of pseudo-peptide hydrazone macrocycles are formed from amino acid-derived building blocks equipped with hydrazide and aldehyde functionalities; a series of experiments confirm that hydrazone formation is reversible and that the libraries are genuinely dynamic.

引用

页码：1575 / 1576

页数：2

共 9 条

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