Organotin esters of N-phthaloylamino acids:: Synthesis, spectroscopic characterization, and biological activities

The synthesis, physical nature and spectroscopic characterization, i.e. CHN analyses as well as the IR, H-1-, C-13-, Sn-119 NMR and Sn-119m Mossbauer spectrometries, of a series of new organotin complexes of N-phthaloylamino acids are described. The monomeric diorganotin complexes possess a trans octahedral geometry. The dimeric tetraorganotin complexes have a penta-coordinate environment. The triphenyltin with N-phthaloylamino acids are assigned a polymeric trigonal bipyramidal geometry in the solid form and a tetrahedral structure in an inert solvent, while tricyclohexyltin with N-phthaloylamino acids complexes possess a tetrahedral geometry. ED50 and biological activities tests were also carried out, which indicated powerful biocidal effects.