Chemical Composition and Antimicrobial Activity of the Volatile Fractions from Leaves and Flowers of the Wild Iraqi Kurdish Plant Prangos peucedanifolia FENZL

被引:17
作者
Brusotti, Gloria [1 ,2 ]
Ibrahim, Mohammed Farhad [1 ,2 ,3 ]
Dentamaro, Alessandra [1 ,2 ]
Gilardoni, Gianluca [2 ,4 ]
Tosi, Solveig [2 ,5 ]
Grisoli, Pietro [1 ,2 ]
Dacarro, Cesare [1 ,2 ]
Guglielminetti, Maria Lidia [5 ]
Hussain, Faiq Hama Saeed [3 ]
Caccialanza, Gabriele [1 ,2 ]
Vidari, Giovanni [2 ,4 ]
机构
[1] Univ Pavia, Dept Drug Sci, I-27100 Pavia, IT, Italy
[2] Univ Pavia, Ctr Studies Ethnobiopharm CISTRE, I-27100 Pavia, IT, Italy
[3] Univ Salahaddin, Coll Sci, Dept Chem, Erbil, Iraq
[4] Univ Pavia, Dept Chem, I-27100 Pavia, IT, Italy
[5] Univ Pavia, Dept Earth Sci & Environm, Mycol Lab, I-27100 Pavia, IT, Italy
关键词
Prangos peucedanifolia; Essential oils; Antimicrobial activity; GAMMA-PYRONE DERIVATIVES; ESSENTIAL OIL; PABULARIA; COUMARINS;
D O I
10.1002/cbdv.201200202
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
070307 [化学生物学]; 071010 [生物化学与分子生物学];
摘要
The volatile fractions isolated from Prangos peucedanifolia Fenzl leaves and flowers were investigated for their phytochemical composition and biological properties. Flower and leaf hydrodistillation afforded 3.14 and 0.49g of yellowish oils in 1.25 and 0.41% yields, respectively, from dry vegetable materials. According to the GC-FID and GC/MS analyses, 36 (99.35% of the total oil composition) and 26 compounds (89.12%) were identified in the two oils, respectively. The major constituents in the flower volatile fraction were -pinene (35.58%), -pinene (22.13%), and -phellandrene (12.54%), while m-cresol (50.38%) was the main constituent of the leaf volatile fraction. The antimicrobial activity was evaluated against several bacterial and fungal strains, on the basis of the minimum inhibitory concentration (MIC) by the micro- and macrodilution methods. The two volatile fractions showed moderate antifungal and antibacterial activities, especially against Trichophyton rubrum (MIC of 2x103g/ml), Streptococcus mutans, Streptococcus pyogenes, and Staphylococcus aureus (MIC1.9x103g/ml for all).
引用
收藏
页码:274 / 280
页数:7
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