Drug-induced bronchiolitis obliterans organizing pneumonia

Several classes of medications cause the bronchiolitis obliterans organizing pneumonia (BOOP) reaction, including the antimicrobials, anticancer agents,. cardiac agents, and anti-inflammatory agents. The BOOP reaction represents an inflammatory response of the lung, and, therefore, is generally reversible by drug cessation or corticosteroid therapy. Organizing pneumonia is a general term that includes BOOP This article includes a review of the clinical findings, radiographic abnormalities, physiologic findings, and management of drug-induced BOOP.