N-(3-benzyloxy-5-methylpyrazin-2-yl)-2-chlorobenzenesulfonamide

被引:4
作者
Ban, SR
Yang, X
Chen, WB
Cheng, XF
Song, HB
机构
[1] Nankai Univ, State Key Lab, Tianjin, Peoples R China
[2] Nankai Univ, Inst Elementoorgan Chem, Tianjin, Peoples R China
来源
ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE | 2006年 / 62卷
关键词
D O I
10.1107/S1600536806011809
中图分类号
O7 [晶体学];
学科分类号
0702 ; 070205 ; 0703 ; 080501 ;
摘要
Molecules of the title compound, C18H16ClN3O3S, crystallize as centrosymmetric dimers, connected by intermolecular N-H (...) O hydrogen bonds. The dimers are interlinked via C-H (...) Cl hydrogen bonds.
引用
收藏
页码:O1713 / O1714
页数:2
相关论文
共 9 条
[1]   CLONING AND EXPRESSION OF A CDNA-ENCODING AN ENDOTHELIN RECEPTOR [J].
ARAI, H ;
HORI, S ;
ARAMORI, I ;
OHKUBO, H ;
NAKANISHI, S .
NATURE, 1990, 348 (6303) :730-732
[2]   New non-peptide endothelin-A receptor antagonists: Synthesis, biological properties, and structure-activity relationships of 5-(dimethylamino)-N-pyridyl-, -N-pyrimidinyl-, -N-pyridazinyl-, and -N-pyrazinyl-1-naphthalenesulfonamides [J].
Bradbury, RH ;
Bath, C ;
Butlin, RJ ;
Dennis, M ;
Heys, C ;
Hunt, SJ ;
James, R ;
Mortlock, AA ;
Sumner, NF ;
Tang, EK ;
Telford, B ;
Whiting, E ;
Wilson, C .
JOURNAL OF MEDICINAL CHEMISTRY, 1997, 40 (06) :996-1004
[3]  
*BRUK AXS INC, 1999, SAINT SHELXTL
[4]  
*BRUK AXS INC, 1998, SMART
[5]   Biphenylsulfonamide endothelin receptor antagonists.: 2.: Discovery of 4′-oxazolyl biphenylsulfonamides as a new class of potent, highly selective ETA antagonists [J].
Murugesan, N ;
Gu, ZX ;
Stein, PD ;
Spergel, S ;
Mathur, A ;
Leith, L ;
Liu, ECK ;
Zhang, RA ;
Bird, E ;
Waldron, T ;
Marino, A ;
Morrison, RA ;
Webb, ML ;
Moreland, S ;
Barrish, JC .
JOURNAL OF MEDICINAL CHEMISTRY, 2000, 43 (16) :3111-3117
[6]  
Sheldrick G. M., 1997, SHELXS 97 PROGRAM CR
[7]  
Sheldrick G.M., 1996, SADABS VERSION 2008
[8]   DISCOVERY AND STRUCTURE-ACTIVITY-RELATIONSHIPS OF SULFONAMIDE ETA-SELECTIVE ANTAGONISTS [J].
STEIN, PD ;
FLOYD, DM ;
BISAHA, S ;
DICKEY, J ;
GIROTRA, RN ;
GOUGOUTAS, JZ ;
KOZLOWSKI, M ;
LEE, VG ;
LIU, ECK ;
MALLEY, MF ;
MCMULLEN, D ;
MITCHELL, C ;
MORELAND, S ;
MURUGESAN, N ;
SERAFINO, R ;
WEBB, ML ;
ZHANG, R ;
HUNT, JT .
JOURNAL OF MEDICINAL CHEMISTRY, 1995, 38 (08) :1344-1354
[9]   Acyl substitution at the ortho position of anilides enhances oral bioavailability of thiophene sulfonamides:: TBC3214, an ETA selective endothelin antagonist [J].
Wu, CD ;
Decker, ER ;
Blok, N ;
Li, J ;
Bourgoyne, AR ;
Bui, H ;
Keller, KM ;
Knowles, V ;
Li, W ;
Stavros, FD ;
Holland, GW ;
Brock, TA ;
Dixon, RAF .
JOURNAL OF MEDICINAL CHEMISTRY, 2001, 44 (08) :1211-1216