Roles of PI3Ks in leukocyte chemotaxis and phagocytosis

被引：217

作者：

Stephens, L ^{[1
]}

Ellson, C ^{[1
]}

Hawkins, P ^{[1
]}

机构：

[1] Babraham Inst, Cambridge CB2 4AT, England

来源：

CURRENT OPINION IN CELL BIOLOGY | 2002年 / 14卷 / 02期

关键词：

D O I：

10.1016/S0955-0674(02)00311-3

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Through selective disruption of phosphoinositide 3-kinase (PI3K) activity and the use of green fluorescent protein tagged derivatives of domains capable of specifically binding the lipid products of PI3Ks in vivo, it has been shown that this family of signalling enzymes have vital and distinct roles in chemotaxis, phagocytosis and phagosome maturation in leukocytes.

引用

收藏

页码：203 / 213

页数：11

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