Thyroid lymphoma: A single institution's experience

被引:60
作者
Ruggiero, FP
Frauenhoffer, E
Stack, BC
机构
[1] Penn State Univ, Coll Med, Div Otolaryngol, Hershey, PA USA
[2] Penn State Univ, Coll Med, Dept Pathol, Hershey, PA USA
[3] Milton S Hershey Med Ctr, Hershey, PA USA
关键词
D O I
10.1016/j.otohns.2005.07.040
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
BACKGROUND: Primary lymphoma of the thyroid gland is uncommon. METHODS: The tumor registry at the Penn State Milton S. Hershey Medical Center was searched for all patients carrying a diagnosis of thyroid lymphoma. All available records for these patients were examined and information regarding patient and tumor characteristics, clinical presentation, interventions, and survival were tabulated. RESULTS: The average age of patient in our series was 67.5 years. There was a 2.7:1 female to male preponderance. Thirteen (60%) patients presented with thyroid nodule(s). Eleven (50%) presented with aerodigestive tract obstructive symptoms. Sixteen (73%) patients had no pre-existing history of thyroid disease; none had known pre-existing Hashimoto's thyroiditis. CONCLUSIONS: The typical thyroid lymphoma patient is female and elderly with painless thyroid enlargement. Compressive symptoms of the aerodigestive tract are common at presentation and may require urgent intervention. Treatment modalities (XRT, CHOP chemotherapy) and outcomes are distinct from other thyroid malignancies.
引用
收藏
页码:888 / 896
页数:9
相关论文
共 28 条
[1]  
Ansell SM, 1999, SEMIN ONCOL, V26, P316
[2]   Primary thyroid lymphoma: Can the diagnosis be made solely by fine-needle aspiration? [J].
Cha, C ;
Chen, H ;
Westra, WH ;
Udelsman, R .
ANNALS OF SURGICAL ONCOLOGY, 2002, 9 (03) :298-302
[3]  
Devine R M, 1981, World J Surg, V5, P33
[4]  
DORIA R, 1994, CANCER-AM CANCER SOC, V73, P200, DOI 10.1002/1097-0142(19940101)73:1<200::AID-CNCR2820730135>3.0.CO
[5]  
2-#
[6]  
FREEMAN C, 1972, CANCER, V29, P252, DOI 10.1002/1097-0142(197201)29:1<252::AID-CNCR2820290138>3.0.CO
[7]  
2-#
[8]  
FRIEDBERG MH, 1994, SURGERY, V116, P1061
[9]  
Ha CS, 2001, CANCER, V91, P629, DOI 10.1002/1097-0142(20010215)91:4<629::AID-CNCR1045>3.0.CO
[10]  
2-Q