The cytolethal distending toxin family

被引:188
作者
Pickett, CL [1 ]
Whitehouse, CA [1 ]
机构
[1] Univ Kentucky, Dept Microbiol & Immunol, Lexington, KY 40536 USA
关键词
D O I
10.1016/S0966-842X(99)01537-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Cytolethal distending toxins are produced by a small but diverse group of bacterial pathogens. This newly discovered toxin family can cause a variety of mammalian cells to become irreversibly blocked in the G2 phase of the cell cycle. How this novel effect is accomplished is unknown but the study of these fascinating toxins promises by a small but diverse group of bacterial pathogens. This newly discovered toxin to reveal new methods of host-pathogen interaction.
引用
收藏
页码:292 / 297
页数:6
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