Nanoengineering Ion Channels for Optical Control

被引:26
作者
Gorostiza, Pau [1 ,2 ]
Isacoff, Ehud Y. [3 ,4 ]
机构
[1] ICREA, IBEC, Barcelona, Spain
[2] CIBER BBN, Barcelona, Spain
[3] Univ Calif Berkeley, Dept Mol & Cell Biol, Lawrence Berkeley Lab, Div Mat Biosci, Berkeley, CA 94720 USA
[4] Univ Calif Berkeley, Lawrence Berkeley Lab, Dept Mol & Cell Biol, Div Phys Biosci, Berkeley, CA 94720 USA
基金
美国国家卫生研究院; 欧洲研究理事会;
关键词
D O I
10.1152/physiol.00018.2008
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Chemical modification with photoisomerizable tethered ligands endows proteins with sensitivity to light. These optically actuated proteins are revolutionizing research in biology by making it possible to manipulate biological processes noninvasively and with unprecedented spatiotemporal resolution.
引用
收藏
页码:238 / 247
页数:10
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