Role of interleukin 8 in the pathogenesis of proliferative vitreoretinopathy

被引：26

作者：

Aksunger, A

Or, M

Okur, H

Hasanreisoglu, B

Akbatur, H

机构：

[1] GAZI UNIV,SCH MED,DEPT OPHTHALMOL,ANKARA,TURKEY

[2] GAZI UNIV,SCH MED,DEPT IMMUNOL,ANKARA,TURKEY

来源：

OPHTHALMOLOGICA | 1997年 / 211卷 / 04期

关键词：

cytokines; interleukin; 8; proliferative vitreoretinopathy; retinal detachment; vitreos;

D O I：

10.1159/000310794

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We investigated the role of interleukin 8 (IL-8) in the pathogenesis of proliferative vitreoretinopathy (PVR). The IL-8 level in the vitreous and the blood of 20 patients with PVR was measured by a specific enzyme-linked immunoassay method. Vitreous from cadaver eyes (n = 20) was used as the control. The IL-8 level in the vitreous was between 31.3 and 65 pg/ml in 40% of eyes with PVR. IL-8 was detected neither in the blood of the patients with PVR nor in the vitreous from cadaver eyes. IL-8 levels in the vitreous did not correlate with either the grade of PVR or the duration of symptoms. These results suggest that IL-8 may play a role in the pathogenesis of PVR.

引用

页码：223 / 225

页数：3

共 29 条

[1] TGF-BETA INDUCES BIMODAL PROLIFERATION OF CONNECTIVE-TISSUE CELLS VIA COMPLEX CONTROL OF AN AUTOCRINE PDGF LOOP [J].