Synthesis and use of 5-vinyl-1,2,4-oxadiazoles as Michael acceptors. A rapid synthesis of the potent muscarinic agonist L-670,548

被引：54

作者：

Macor, JE

Ordway, T

Smith, RL

Verhoest, PR

Mack, RA

机构：

[1] Department of Chemistry, Astra Arcus USA, Rochester, NY 14602

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1996年 / 61卷 / 10期

关键词：

D O I：

10.1021/jo9603340

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[No abstract available]

引用

页码：3228 / 3229

页数：2

共 4 条

[1]

SAUNDERS J, 1989, TRENDS PHARMACOL SCI, P70

[2] SYNTHESIS AND SEROTONERGIC ACTIVITY OF 5-(OXADIAZOLYL)TRYPTAMINES - POTENT AGONISTS FOR 5-HT(1D) RECEPTORS [J].

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[3] SYNTHESIS AND BIOLOGICAL-ACTIVITY OF 1,2,4-OXADIAZOLE DERIVATIVES - HIGHLY POTENT AND EFFICACIOUS AGONISTS FOR CORTICAL MUSCARINIC RECEPTORS [J].

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HARLEY, EA .

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[4] NOVEL BENZODIAZEPINE RECEPTOR PARTIAL AGONISTS - OXADIAZOLYLIMIDAZOBENZODIAZEPINES [J].

WATJEN, F ;

BAKER, R ;

ENGELSTOFF, M ;

HERBERT, R ;

MACLEOD, A ;

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MERCHANT, K ;

MOSELEY, J ;

SAUNDERS, J ;

SWAIN, CJ ;

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SPRINGER, JP .

JOURNAL OF MEDICINAL CHEMISTRY, 1989, 32 (10) :2282-2291

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