Frequency and characteristics of hospital admissions associated with drug-related problems in paediatrics

被引:61
作者
Easton, KL
Chapman, CB
Brien, JE
机构
[1] Univ Sydney, Fac Pharm, Sydney, NSW 2006, Australia
[2] Monash Univ, Victorian Coll Pharm, Parkville, Vic 3052, Australia
关键词
drug-related problems; hospital admissions; non-adherence; paediatrics;
D O I
10.1111/j.1365-2125.2003.02052.x
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Aim To determine the frequency of paediatric hospital admissions associated with drug-related problems (DRPs) at two Australian hospitals. Methods The investigator and ward pharmacists prospectively screened eligible patients. A multidisciplinary panel reviewed data and established causality, preventability and clinical significance classifications. Results Over 22 weeks of data collection, a total of 1 1 564 patients were admitted, 2933 met eligibility criteria. of those eligible, 127 (4.3%, 95% confidence interval (CI) 3.6, 5.0] were judged to have hospital admissions associated with DRPs. Direct costs associated with DRPs identified totalled pound100 707. of the 81 cases assessed for preventability, 46.9% were deemed preventable, Conclusions This research has provided information on the nature and characteristics of paediatric DRPs associated with hospital admissions.
引用
收藏
页码:611 / 615
页数:5
相关论文
共 17 条
[1]   PROSPECTIVE STUDY OF EPIDEMIOLOGY OF ADVERSE DRUG-REACTIONS IN PEDIATRIC HEMATOLOGY AND ONCOLOGY PATIENTS [J].
COLLINS, GE ;
CLAY, MM ;
FALLETTA, JM .
AMERICAN JOURNAL OF HOSPITAL PHARMACY, 1974, 31 (10) :968-975
[2]   The incidence of drug-related problems as a cause of hospital admissions in children [J].
Easton, KL ;
Parsons, BJ ;
Starr, M ;
Brien, JAE .
MEDICAL JOURNAL OF AUSTRALIA, 1998, 169 (07) :356-359
[3]   Emergency department attendances associated with drug-related problems in paediatrics [J].
Easton-Carter, KL ;
Chapman, CB ;
Brien, JE .
JOURNAL OF PAEDIATRICS AND CHILD HEALTH, 2003, 39 (02) :124-129
[4]   COST-OF-ILLNESS METHODOLOGY - A GUIDE TO CURRENT PRACTICES AND PROCEDURES [J].
HODGSON, TA ;
MEINERS, MR .
MILBANK MEMORIAL FUND QUARTERLY-HEALTH AND SOCIETY, 1982, 60 (03) :429-462
[6]   DRUG-RELATED MORBIDITY AND MORTALITY - A COST-OF-ILLNESS MODEL [J].
JOHNSON, JA ;
BOOTMAN, JL .
ARCHIVES OF INTERNAL MEDICINE, 1995, 155 (18) :1949-1956
[7]   Frequency of adverse drug reactions in children:: A prospective study [J].
Jonville-Béra, AP ;
Giraudeau, B ;
Blanc, P ;
Beau-Salinas, F ;
Autret-Leca, E .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 53 (02) :207-210
[8]   Drug-related hospitalization at a tertiary teaching center in Lebanon: Incidence, associations, and relation to self-medicating behavior [J].
Major, S ;
Badr, S ;
Bahlawan, L ;
Hassan, G ;
Khogaoghlanian, T ;
Khalil, R ;
Melhem, A ;
Richani, R ;
Younes, F ;
Yeretzian, J ;
Khogali, M ;
Sabra, R .
CLINICAL PHARMACOLOGY & THERAPEUTICS, 1998, 64 (04) :450-461
[9]   A prospective study of adverse drug reactions as a cause of admission to a paediatric hospital [J].
MartinezMir, I ;
GarciaLopez, M ;
Palop, V ;
Ferrer, JM ;
Estan, L ;
Rubio, E ;
MoralesOlivas, FJ .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1996, 42 (03) :319-324
[10]   DRUG-RELATED HOSPITAL ADMISSIONS [J].
MCKENNEY, JM ;
HARRISON, WL .
AMERICAN JOURNAL OF HOSPITAL PHARMACY, 1976, 33 (08) :792-795